Protein Modification Reagents
Sigma Aldrich Fine Chemicals Biosciences LpodsqR StyreneMalec A100MG
Lipodisq(R) polymers contain styrene and maleic acid monomer units. This product is the pre-hydrolyzed form of the SMA polymer with the styrene and maleic acid monomers. These polymer-lipid complexes are mainly generated by detergent-free methods.
Chemscene ChemScene | N3-PEG4-C2-NHS ester | 250MG | CS-0105092 | 0.98 | 944251-24-5| MFCD13184948 | 388.37
ChemScene | N3-PEG4-C2-NHS ester | 250MG | CS-0105092 | 0.98 | 944251-24-5| MFCD13184948 | 388.37
Chemscene ChemScene | Bromo-PEG2-C2-azide | 250MG | CS-0108237 | 0.97 | 530151-56-5| MFCD25424115 | 238.08
ChemScene | Bromo-PEG2-C2-azide | 250MG | CS-0108237 | 0.97 | 530151-56-5| MFCD25424115 | 238.08
Medchemexpress LLC Cholesterol-PEG 600 | 69068-97-9 | 1,055.60 g/mol | C68H110O8 | 1 G
Cholesterol-PEG 600 is a cholesterol-terminated polyethylene glycol reagent (average PEG MW ~600) used in life-science research to modify lipid assemblies and improve amphiphilic conjugation. It is supplied as an oil (off-white to light yellow) for formulation into liposomes, nanoparticles, and other delivery systems. For research use only.
Kyfora Bio Polyethylene glycol 1450
Polyethylene glycol (PEG) is a water-soluble biologically inert polymer that has a number of biological and pharmaceutical applications Specifically PEG1450 can be used as an excipient in pharmaceutical products or as a coating on nanoparticles to prevent opsonization in vivo It can also be used for purification of plasmid DNA The polymer chains are hydroxyl terminated at both ends
Medchemexpress LLC Poly(lactic-co-glycolic acid)-block-poly(ethylene glycol)-maleimide | 95.0% | PLGA 20 kDa; PEG 5.0 kDa | 10 MG
PLGA-PEG-MAL is a thiol-reactive block copolymer comprised of poly(lactic-co-glycolic acid) and polyethylene glycol terminated with a maleimide group. The product is specified with a ~20 kDa PLGA block and a ~5.0 kDa PEG block (LA:GA 40:60) and is intended for research use in nanoparticle formulation, surface functionalization, and conjugation of thiol-containing ligands.
- Polymeric block copolymer with maleimide functional group for thiol conjugation.
- PLGA block ~20 kDa; PEG block ~5.0 kDa, LA:GA ratio 40:60.
- Suitable for nanoparticle formulation and drug delivery research.
- Soluble in DMSO for formulation and conjugation workflows.
- Reported purity approximately 95.0%.
- Supplied in small research quantities (for example, 10 mg packs).
Medchemexpress LLC 3H-indolium di-sulfo Cy5 alkyne sodium salt | 1617497-19-4 | 99.0% | 701.83 | C35H40N3NaO7S2 | 10 MG
DiSulfo-Cy5 alkyne is a di-sulfonated Cy5-family fluorescent dye functionalized with a terminal alkyne for bioorthogonal click chemistry. It is water-soluble and intended for covalent conjugation to azide-bearing biomolecules via copper-catalyzed azide-alkyne cycloaddition (CuAAC), enabling fluorescent labeling for imaging and detection in biochemical assays.
- Water-soluble, di-sulfonated Cy5 fluorophore.
- Terminal alkyne for copper-catalyzed azide-alkyne click chemistry.
- Suitable for labeling proteins, nucleic acids, and small molecules.
- High purity (~99.0%) with characterized molecular weight.
- Supplied as a 10 MG vial for laboratory use.
- Molecular formula C35H40N3NaO7S2 and molecular weight 701.83.
Medchemexpress LLC Bi2536-peg2-halo | 99.4% | 790.39 g/mol | C39H60ClN7O8 | 10 MG
A bifunctional chemical probe that links a PLK1 inhibitor to a Halo-tag ligand via a PEG2 spacer, designed for cellular target engagement and imaging studies.
- Combines PLK1 inhibitory activity with Halo-tag targeting.
- High stated purity (99.44%).
- Soluble in DMSO at 100 mg/mL for preparing concentrated stocks.
- Suitable for cellular target validation and imaging of Halo-tag fusion proteins.
- Available in small research pack sizes, including 10 mg, for screening and probe studies.
Medchemexpress LLC Dspe-peg-mannose | 1829524-73-3 | 90.0% | 2000 Da (average) | (C2H4O)nC57H102N3O16PS | 10 MG
DSPE-PEG(2000)-Mannose is a mannose-terminated DSPE-PEG lipid conjugate used to prepare mannose-functionalized liposomes and lipid nanoparticles for receptor-mediated targeting. It is intended for research use to enhance targeting of antigen-presenting cells and to improve vaccine or drug delivery performance.
- Lipid-PEG conjugate with a terminal mannose for mannose-receptor targeting.
- Average molecular weight ~2000 Da.
- Purity 90.0%.
- Appearance: white to off-white solid.
- Storage: powder -20°C (3 years); in solvent -80°C (6 months), -20°C (1 month).
- Suitable for constructing mannose-functionalized liposomes and lipid nanoparticles for targeting applications.
- CAS number 1829524-73-3.
AG Scientific Inc Dithiothreitol, DTT, 5 G
Dithiothreitol (DTT), is a small-molecule redox reagent, known as Cleland's reagent, that forms a six-member ring with an internal disulfide bond. It has a redox potential of -0.33 V at pH 7. The reduction of typical disulfide bond proceeds by two sequential thiol-disulfide exchange reactions.DTT is effective in buffers to reduce protein disulfide bonds prior to SDS-PAGE. It can protect protein sulfhydryls and restore enzyme activity lost by oxidation.CAS Number: 3483-12-3Molecular Weight: 154.2Chemical Formula: C4H10O2S2Solubility: 10% solution in water. Clear and colorlessStorage Temperature: 2-8CResearch or further manufacturing use only, not for food or drug use.
Medchemexpress LLC DSPE-PEG-DBCO | 99.9% | 2000 (average) | 25 MG
DSPE-PEG-DBCO (MW 2000) is a PEGylated phospholipid conjugate bearing a dibenzocyclooctyne (DBCO) group. It serves as a click-chemistry-capable lipid for incorporation into lipid nanoparticles or micelles and for rapid, copper-free conjugation to azide-containing molecules via strain-promoted alkyne-azide cycloaddition (SPAAC). Typical uses include nanoparticle formulation, surface PEGylation, and bioconjugation.
- PEGylated phospholipid with average molecular weight 2000.
- DBCO functional group enables copper-free SPAAC with azides.
- Suitable for lipid nanoparticle and micelle formulation.
- Facilitates bioconjugation and surface modification.
- High purity (reported 99.9%) for research applications.
Medchemexpress LLC DSPE-PEG-amine (ammonium) | 474922-26-4 | 99.5% | 1000 (average) | (C2H4O)nN2O10P.NH3 | 50 MG
DSPE-PEG-Amine, MW 1000 (ammonium) is an amine-terminated PEGylated phospholipid used to functionalize liposomes and nanoparticle surfaces for bioconjugation and targeted delivery. The terminal primary amine enables covalent coupling to aldehydes and activated esters, facilitating stable surface modification.
- Amine-terminated PEGylated phospholipid suitable for liposome and nanoparticle functionalization.
- Average molecular weight ~1000, providing a balance between hydrophilicity and anchoring.
- High purity (~99.5%) for reproducible conjugation and formulation performance.
- White to off-white solid, convenient for storage and handling.
- Storage: store sealed at -20°C; in solvent, -80°C (6 months) or -20°C (1 month).
- Terminal primary amine enables covalent conjugation to aldehydes or activated esters.
Medchemexpress LLC DSPE-PEG-azide | 90.6% | 2000 (average) | C44H85N4O10P | 10 MG
DSPE-PEG-azide (average MW 2000) is an azide-functionalized phospholipid-polyethylene glycol conjugate used to introduce reactive azide handles on lipid assemblies. It enables click-chemistry bioconjugation for surface modification of liposomes, micelles, and nanoparticles in drug-delivery and biofunctionalization workflows.
- Provides an azide functional group compatible with CuAAC and SPAAC reactions.
- Facilitates stable PEGylation for improved colloidal stability and circulation.
- Suitable for incorporation into liposomes, micelles, and other lipid nanoparticles.
- Supplied as a small-quantity reagent for research-scale conjugation workflows.
- Characterized by an average molecular weight of 2000 and a purity of 90.6%.